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目的研究高频彩超结合剪切波弹性成像对甲状腺癌的诊断价值。方法以60例行甲状腺检查的甲状腺结节患者为研究对象,所有患者首先接受高频彩超检查,判别甲状腺结节的良恶性。3个月后,所有患者接受剪切波弹性成像检查,根据检查结果判断结节良恶性。另外,结合两种方法的检查结果 ,综合评价患者的病情,判断结节的良恶性。所有患者进行病理学检查确诊。计算高频彩超、剪切波弹性成像以及高频彩超结合剪切波弹性成像(联合检查)的检测准确性、敏感性、特异性,并进行比较。结果病理学结果显示:60例患者中,有40例为良性结节,20例为恶性结节。影像学结果显示:高频彩超的敏感性、特异性、准确性分别为88.2%、88.4%和88.3%,剪切波弹性成像的敏感性、特异性、准确性分别为94.1%、90.7%和91.7%,稍高于高频彩超的诊断结果。联合检查的诊断敏感性、特异性、准确性分别为95.0%、97.5%、96.7%,显著优于高频彩超和剪切波弹性成像检查结果,差异有统计学意义(P<0.05)。结论高频彩超结合剪切波弹性成像用于诊断甲状腺癌有重要参考价值,其判断甲状腺结节良恶性的准确性、灵敏度和特异性较高,诊断结果可靠,值得临床推广应用。
Objective To study the diagnostic value of high frequency color Doppler ultrasound combined with shear wave elastography in the diagnosis of thyroid cancer. Methods Totally 60 patients with thyroid nodules undergoing thyroid examination were selected as the study subjects. All patients underwent first-line high-frequency color Doppler ultrasound examination to distinguish between benign and malignant thyroid nodules. Three months later, all patients underwent shear wave elastography and the nodules were judged as benign and malignant according to the examination results. In addition, combined with the two methods of test results, a comprehensive evaluation of the patient’s condition, to determine the benign and malignant nodules. All patients were diagnosed pathologically. The accuracy, sensitivity and specificity of high frequency ultrasound, shear wave elastography and high frequency color Doppler ultrasound combined with shear wave elastography (combined examination) were calculated and compared. Results The pathology results showed that of 60 patients, 40 were benign nodules and 20 were malignant nodules. The sensitivity, specificity and accuracy of high frequency ultrasound were 88.2%, 88.4% and 88.3% respectively. The sensitivity, specificity and accuracy of shear wave elastography were 94.1% and 90.7% respectively 91.7%, slightly higher than the diagnosis of high frequency ultrasound. The diagnostic sensitivity, specificity and accuracy of the combined examination were 95.0%, 97.5% and 96.7% respectively, which were significantly better than the results of high frequency color Doppler ultrasound and shear wave elastography. The difference was statistically significant (P <0.05). Conclusion High-frequency color Doppler ultrasound combined with shear-wave elastography is an important reference value for the diagnosis of thyroid cancer. The sensitivity, specificity and sensitivity of thyroid nodules in diagnosis of thyroid nodules are good. The diagnosis is reliable and worthy of clinical application.