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本文报导13例实体瘤病人(肺癌6例,乳癌4例,甲状腺癌1例、结肠癌2例,在手术切除肿瘤后,应用短小棒状杆菌(CP)治疗,9人接受2.5mg/m~2加于250ml葡萄糖中滴注,4人皮下注射4mg,15名正常人作为对照、进行单核细胞功能体外检测。用表面吸附特异IgG抗体的羊红细胞(EA)或表面吸附IgM和补体的人红细胞(HEAC)的结合活力来测定单核细胞受体活性。在单核细胞上盖上一层0.5％EA和0.5％HEAC贴到盖玻片上,放30分后洗涤,用甲醇固定,利什曼溶液染色,测定100个单核细胞对EA和HEAC的粘附或吞噬、称“粘附指数”。在用CP治疗前及一疗程静滴治疗后二天,病人对EA的粘附指数为
This article reports 13 patients with solid tumors (6 cases of lung cancer, 4 cases of breast cancer, 1 case of thyroid cancer, 2 cases of colon cancer, after the surgical removal of the tumor, the application of Corynebacterium parvum (CP) treatment, 9 were 2.5mg / m ~ 2 Added to 250ml glucose instillation, 4 subcutaneous injection of 4mg, 15 normal control as monocyte function in vitro detection with specific surface IgG adsorption of sheep red blood cells (EA) or surface adsorption of IgM and complement human red blood cells (HEAC) to determine monocyte receptor activity.On the monocytes covered with a layer of 0.5% EA and 0.5% HEAC paste on the cover glass, after 30 minutes to wash, fixed with methanol, Leishman Solution staining to determine the attachment of 100 monocytes to EA and HEAC adhesion or phagocytosis, called “adhesion index.” Before treatment with CP and a course of treatment two days after intravenous infusion, the patient’s adhesion index to EA was