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用“放射受体分析法”研究强的松龙、长春新碱及ＤＨＡＱ对ＨＬ－６０细胞株糖皮质激素受体（ＧＣＲ）的影响，结果发现：①在一定条件下，强的松龙、ＤＨＡＱ能明显地降低ＧＣＲ含量和亲和力，且对ＧＣＲ含量的影响呈明显的时间、药物浓度依赖关系；②相同条件下，长寿新碱亦能一定程度地降低ＧＣＲ含量，但对亲和力影响不明显；③当强的松龙分别与ＤＨＡ０、长春新碱合用时，显示出对ＧＣＲ含量的降低效应有明显的协同作用。
Radix receptor analysis was used to study the effects of prednisolone, vincristine and DHAQ on glucocorticoid receptor (GCR) in HL-60 cells. The results showed that: (1) Under certain conditions, prednisolone, DHAQ can significantly reduce the GCR content and affinity, and the effect on GCR content was significantly time-dependent drug dependence; ② under the same conditions, longevity of new alkali can also reduce the level of GCR, but the affinity was not obvious; ③ When prednisolone, respectively, with DHA0, vincristine combined, showed a significant synergistic effect on the reduction of GCR content.