血浆置换术是通过对血液成份的分离,去除患者血液中的异常成份,置入正常的血液成份以清除致病物质,配合药物治疗而达到临床治疗的目的。80年代初期以来,血浆置换术已逐渐应用于临床,并在治疗难治病方面,取得良好成绩,现将我院应用血浆置换术治疗2例肝豆状核变性(HLD)结果报告如下:病例1女,20岁,四肢粗大震颤,进行性加重4年,精神异常3月余入院。3年前诊断为肝豆状核变性,曾用青霉胺、硫酸锌、654—2等药物 Plasma exchange is through the separation of blood components to remove abnormal blood components of patients, into the normal blood components to clear the pathogenic substances, with drug treatment and achieve the purpose of clinical treatment. Since the early 80’s, plasmapheresis has been gradually applied to clinical and treatment of refractory disease, and achieved good results, now our hospital plasmapheresis in the treatment of 2 cases of hepatolenticular degeneration (HLD) results are reported as follows: cases 1 female, 20 years old, limbs thick tremor, aggravating 4 years, mental disorders more than 3 months admitted to hospital. 3 years ago, diagnosed as Wilson’s disease, had penicillamine, zinc sulfate, 654-2 and other drugs