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１９９０年５月１日～１９９４年４月３０日，对在我院确诊为智力低下（ＭＲ）患者中与遗传因素有关的１６２例（占１６％）进行分析。结果：农村７７．８％，城市２２．２％；男女之比２．４５：１；轻度３８．３％，重度６１．７％；染色体病中２１三体最多占６３．４％；脆性Ｘ综合征占２４％，其中女性２例，均为重度ＭＲ。先天代谢疾病主要是克汀病和苯丙酮尿症，占２２．２％。遗传变性病占病因的２５．３％，其中结节性硬化２７例占１６．７％。提示：遗传因素所致的ＭＲ重度较多，如能早期诊断、早期干预，可以减少ＭＲ的发生和减轻智低程度。
From May 1, 1990 to April 30, 1994, 162 cases (16%) of genetic factors related to the diagnosis of mental retardation (MR) in our hospital were analyzed. Results: 77.8% in rural areas, 22.2% in urban areas, 2.45: 1 in male and female ratio, 38.3% in mild cases, 61.7% in severe cases, and 21.4% in chromosome diseases. Syndrome X accounted for 24%, including 2 females, were severe MR. Congenital metabolic diseases are mainly cretinism and phenylketonuria, accounting for 22.2%. Genetic degenerative disease accounted for 25.3% of the cause, of which 27 cases of tuberous sclerosis accounted for 16.7%. Tip: genetic factors caused by MR more severe, if early diagnosis, early intervention, can reduce the occurrence of MR and reduce the level of intellectual loss.