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患者,男,75岁。因上腹饱胀不适半个月,胃镜示:胃小弯溃疡。无肾脏疾病患史,给予雷尼替丁0.15g一日二次。服药后48小时出现走路步态不稳。72小时后要人扶持才能行走,而来院求诊。体检:血压16/7kpa,神清、颈软、心肺正常。腹平、剑下轻压痛,无肌卫及反跳痛,余腹无压痛。两下肢肌张力增高,腱反射稍亢进。患者近期内未服用其它药物,考虑雷尼替丁引起下肢共济失调。立即停药,改用硫糖铝1.0g,一日三次。于停药后24小时症状减轻,48小时后消失。随访一个月,上述症状
Patient, male, 75 years old. Abdominal distension due to abdominal discomfort for half a month, gastroscopy showed: gastric ulcer. No history of kidney disease, giving ranitidine 0.15g twice a day. 48 hours after taking a walk gait instability. After 72 hours people support to walk, but to hospital for treatment. Physical examination: blood pressure 16 / 7kpa, God clear, soft neck, normal heart and lung. Abdominal flat, light sword tenderness, no muscle Wei and rebound tenderness, no abdominal tenderness. Lower limb muscle tone increased tendon reflex slightly hyperthyroidism. Patients have not taken other drugs in the near future, consider ranitidine caused lower extremity ataxia. Immediate withdrawal, use sucralfate 1.0g, three times a day. Symptoms were relieved 24 hours after drug withdrawal and disappeared after 48 hours. Followed up for a month, the above symptoms