脱氧穿心莲内酯(穿心莲甲素、deoxyandrographolide)、穿心莲内酯(穿心莲乙素、andrographolide)、穿心莲甙(穿心莲丙素、neoandrographolide)及脱水穿心莲内酯(穿心莲丁素、deoxydidehydroandrographolide)是穿心莲地上部分含有的4种内酯成分。虽曾报告这些内酯化合物对多种感染性疾病都具有不同程度的疗效,但现在药厂生产及临床应用者大多为穿心莲乙素或总内酯制剂。已有一些研究指出这些内酯在穿心莲叶中的含量相差甚大,并随产地、采收季节、储存时间及条件而有较大的变化,因而弄清这4种内酯化合物在药理作用上 Deoxyandrographolide, andrographolide, andrographolide and neoandrographolide and deoxydidehydroandrographolide are the compounds that are contained in the aerial part of Andrographis paniculata Four lactone components. Although these lactone compounds have been reported to have varying degrees of efficacy against a variety of infectious diseases, most of the pharmaceutical and clinical applications nowadays are andrographolide or total lactone formulations. Some studies have pointed out that these lactones in the lotus leaf content varies widely, and with the origin, harvest season, storage time and conditions and have a greater change, and thus clear four pharmacological effects of these lactone compounds