局限性黄斑转位手术的实验研究

来源 :中华眼底病杂志 | 被引量 : 0次 | 上传用户:gyl722
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目的 建立局限性黄斑转位手术 (limited macular translocation,L MT)的兔眼模型 ,探讨L MT的并发症、适应证及可预测性。 方法 建立 L MT的兔眼模型 ,并按巩膜缩短距离分为 4 .5、3.5 mm组 ,观察视网膜转位效果 (距离和方向 )及并发症 ;手术后 1个月松解 4只兔眼的巩膜缩短缝线 ,并在松解巩膜缩短缝线前后测量角膜地形图以了解角膜散光的变化 ;视网膜光凝标记 4只有色素兔的视网膜和脉络膜 ,观察光凝造成的神经视网膜 -视网膜色素上皮 (retinal pigment epithelium,RPE)粘连对手术效果的影响。 结果  L MT的成功率达 86 .7% ,视网膜转位距离为 6 10~ 2 6 90 μm,平均转位距离为 (1395±6 36 ) μm,视网膜转位角度 α为 10~ 38°,平均转位角度为 (2 2 .7± 8.3)°,巩膜缩短 4 .5、3.5 mm组的转位距离差异无显著性意义 (P>0 .0 5 )。并发症主要有眼内出血、视网膜裂孔、角膜散光等。巩膜缩短缝线松解后角膜散光变小、变规则 ,而视网膜转位未回退。视网膜光凝造成的神经视网膜 - RPE粘连使神经视网膜难以分离 ,易产生视网膜裂孔。 结论  L MT的兔眼模型获得了解剖转位成功 ,并发症较少 ;视网膜转位方向是影响手术效果的重要因素 ;巩膜缩短缝线松解手术可以安全、有效地减轻手术后的角膜散光 ;对? Objective To establish a rabbit eye model with limited macular translocation (L MT) and investigate the complications, indications and predictability of L MT. Methods The rabbit model of L-MT was established and divided into 3.5 and 3.5 mm groups according to the scleral shortening distance. The retinal translocation effects (distance and direction) and complications were observed. Four rabbits were detached one month after surgery Sclera to shorten the suture, and in the release of the scleral suture before and after the shortening of the corneal topography to understand changes in corneal astigmatism; retinal photocoagulation 4 pigmented retinal and choroid mark the observation of photocoagulation caused by neural retinal - retinal pigment epithelium ( retinal pigment epithelium (RPE) on the effect of surgery. Results The success rate of L MT was 86.7%, the retinal translocation distance was 6 10 ~ 2 6 90 μm, the mean translocation distance was (1395 ± 6 36) μm, retinal translocation angle α was 10 ~ 38 °, the average There was no significant difference in the translocation distances between the 3.5 and 3.5 mm groups (P> 0.05) for the translocation angle of (22.7 ± 8.3) ° and the shortening of the sclera (P> 0.05). Complications are mainly intraocular hemorrhage, retinal tears, corneal astigmatism and so on. Scleral shortened suture astigmatism after astigmatism smaller, change rules, and retinal transposition did not back down. Retinal photocoagulation caused by nerve retinal - RPE adhesions make the neural retina difficult to separate, easy to produce retinal breaks. CONCLUSION: The rabbit model of L-MT has achieved successful anatomical transposition with fewer complications. The direction of retinal translocation is an important factor affecting the surgical outcome. Scleral buckling and suture release can safely and effectively reduce corneal astigmatism after surgery. Correct?
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