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尽管毛圆线虫对苯并咪唑类驱蠕虫药的抗性发展缓慢,但现在抗性的增长已成为一个问题。由于苯并咪唑类驱蠕虫药的抗性可能比目前预想的更广泛,因此普查抗性还需要大规模进行。抗性检测的主要障碍之一是缺乏测定药物疗效降低的快速、可靠、价廉的方法。已有的粪便虫卵减数法和某些能用于苯并咪唑类抗性检测的体外法,如虫卵孵化法、试管-捆绑法以及目前最可靠的抑制蠕虫疗效试验法,均不尽满意。因而不得不依赖生化检测的方法,包括对抗性株和敏感株
Despite the slow development of resistance to benzimidazole worms in Trichoplusia, growth of resistance has now become a problem. Census resistance needs to be carried out on a large scale as the resistance of benzimidazole worms may be more extensive than currently envisaged. One of the major obstacles to resistance testing is the lack of a fast, reliable and inexpensive method of determining the efficacy of a drug. Existing excrement egg subtraction method and some can be used for the detection of benzimidazole resistance in vitro methods, such as egg hatching method, tube - binding method and currently the most reliable method of inhibiting worm efficacy test, not all satisfaction. Thus having to rely on biochemical assays, including confrontational and susceptible strains