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目的 调查中国长沙地区女性不同骨胳部位与年龄相关的骨密度 (BMD)、累积骨丢失和骨质疏松症 (OP)的患病率。方法 用DXAQDR45 0 0A型扇形束骨密度仪测量 1818例 15～ 96岁女性腰椎前后位 (AP)和仰卧侧位、髋部及前臂的BMD。结果 按每 5岁年龄分组分析的结果显示 ,不同骨胳部位的峰值BMD分别发生在 2 0～ 2 4岁至 40～ 44岁之间 ,其中髋部的大转子和Ward’s区最早 (2 0～ 2 4岁 ) ,前臂 1/ 3处最晚 (40～ 44岁 ) ;到≥ 80岁累积骨丢失率最多的部位是Ward’s区(- 6 6 .8% ) ,最少的部位为前臂 1/ 3处 (- 33.2 % ) ;至少有一个骨胳区域的BMD值达到OP标准的发生率是 :30～ 39岁为 (0 .5± 0 .5 ) % ,40～ 49岁为 (5 .0± 4.5 ) % ,5 0～ 5 9岁为 (2 0 .9± 11.7) % ,6 0～6 9岁为 (5 4.9± 2 1.1) % ,70～ 79岁为 (72 .4± 18.6 ) % ,≥ 80岁为 (85 .6± 12 .0 ) %。结论 不同骨胳部位峰值BMD发生的年龄、累积骨丢失率和OP患病率存在明显差别。测量部位不同 ,OP的患病率不同 ,随年龄增长的OP患病率也不同。腰椎侧位是早期诊断OP的最敏感部位。
Objective To investigate the prevalence of age-related bone mineral density (BMD), cumulative bone loss, and osteoporosis (OP) at different bone sites in women in Changsha, China. Methods BMD of 1818 cases of female lumbar anteroposterior (AP) and supine lateral position, hip and forearm were measured with a DXAQDR 4500 azimuth beam bone densitometer. Results According to the results of the age group analysis of each 5-year-old group, the peak BMD of different skeletal sites occurred between the ages of 20-24 years and 40-44 years, with the greater trochanter of the hip and Ward’s area being the earliest (2 0- (2 4 years old), the youngest forearm 1 / 3 (40 to 44 years old); to ≥ 80 years old cumulative bone loss was Ward’s area (- 6 6 .8%), the lowest part of the forearm 1/3 (- 33.2%); The incidence of BMD values reaching OP criteria in at least one skeletal region is (0.5 ± 0.5) % for 30 to 39 years old, and (5.0) ± for 40 to 49 years old. 4.5) %, 5 0-9 9 years old (2 0 . 9± 11.7) %, 6 0- 6 9 years old (5 4.9 ± 2 1.1) %, 70-79 years old (72 .4 ± 18.6) % ≥ 80 years old (85.6±12.0%)%. Conclusion There are significant differences in age, cumulative bone loss rate, and OP prevalence of peak BMD at different sites. Different sites have different prevalences of OP, and the prevalence of OP increases with age. Lateral lumbar spine is the most sensitive site for early diagnosis of OP.