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[目的]探讨CEA在结直肠癌微转移的表达及意义。[方法]采用免疫组化LSAB法对54例未发现转移的287个淋巴结重新制片做CEA检测及常规染色。[结果]8例中15个淋巴结发现微转移，所有的转移灶CEA均阳性。[结论]CEA检测可有助于淋巴结内微转移灶的检出，对临床分期及预后的判断具有重要的意义。
[Objective] To investigate the expression and significance of CEA in micrometastasis of colorectal cancer. [Method] The immunohistochemical LSAB method was used to reexamine 287 lymph nodes in 54 cases without CEA for CEA detection and routine staining. [Results] Micrometastases were found in 15 of the 8 cases and all the metastases CEA were positive. [Conclusion] The detection of CEA can be helpful for the detection of micrometastasis in lymph nodes, which is of great significance for judging the clinical stage and prognosis.