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目的探讨前列腺软斑症的临床病理特征、诊断与鉴别诊断。方法分析2012年7月17日就诊的1例前列腺软斑症的临床表现及病理学特征,并复习相关文献。结果患者为老年男性,血清前列腺特异抗原升高,临床与影像检查疑为前列腺癌。穿刺活体组织检查见大片组织细胞样细胞,细胞质丰富、浅染;细胞内、外可见特征性的Michaelis-Gutmann小体,von Kossa钙染色、普鲁士蓝铁染色和高碘酸希夫染色阳性。结论前列腺软斑症较少见,临床、影像与病理学上均要与前列腺癌鉴别,知晓该病并熟悉其病理特征是正确诊断的关键。
Objective To investigate the clinical and pathological features, diagnosis and differential diagnosis of benign prostatic hyperplasia. Methods The clinical manifestations and pathological features of 1 case of benign prostatic hyperplasia who were treated on July 17, 2012 were analyzed and the related literatures were reviewed. Results Patients were elderly men, serum prostate specific antigen increased, clinical and imaging suspected prostate cancer. Biopsy biopsy showed large tissue cell-like cells, rich cytoplasm, light staining; intracellular and extracellular visible characteristic Michaelis-Gutmann bodies, von Kossa calcium staining, Prussian blue iron staining and periodic acid Schiff staining positive. Conclusions Prostatic hyperplasia is rare, and its clinical, imaging and pathological features should be differentiated from that of prostate cancer. Knowing the disease and familiar with its pathological features are the keys to correct diagnosis.