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横纹肌溶解综合征(rhabdomyolysis,RM)指一系列因素影响横纹肌细胞膜、膜通道及其能量供应的多种遗传性或获得性疾病导致的横纹肌损伤,常伴有威胁生命的代谢紊乱,30%患者可能出现急性肾功能衰竭。该类患者病死率高,幸存者多有不同程度的后遗症。横纹肌溶解症治疗的关键在于去除诱因,早期应输入大量晶体液,促进肌红蛋白排出,并碱化尿液,维持尿p H 6.5~7.0。一旦发现肌酐和尿素逐渐升高,即使尿量无
Rhabdomyolysis (RM) refers to a series of factors that affect striated muscle damage caused by a variety of hereditary or acquired diseases of striated muscle cell membranes, membrane channels, and their energy supply, often accompanied by life-threatening metabolic disorders, and 30% of patients may Acute renal failure. Such patients with high mortality, survivors have varying degrees of sequelae. The key to the treatment of rhabdomyolysis is to remove the incentive to enter a large amount of early liquid crystal, and promote the discharge of myoglobin, and alkalinization of urine to maintain urine p H 6.5 ~ 7.0. Once found creatinine and urea gradually increased, even if no urine output