论文部分内容阅读
止咳平喘口服液由麻黄、五味子、细辛、甘草4味中药经乙醇渗滤加工制成的口服制剂,麻黄系君药。制剂中麻黄碱的比色法测定已有报道[1～3],本文采用碱化萃取-比色的方式测定止咳平喘口服液中麻黄碱的含量,操作简便、快速,结果满意。1 仪器与试药 岛津UV-2100紫外分光光度计;盐酸麻黄碱（新疆和硕麻黄素制品责任有限公司,批号990301,山东省医药公司分装,含量99.3％）;盐酸麻黄碱对照品（中国药品生物制品检定所,714-9202）;止咳平喘口服液（医院制剂）;二硫化碳（AR）;其他试剂均为分析纯。2 提取方法的选择 取盐酸麻黄碱溶液（200μg·mL-1）5.0mL,置分液漏斗中,平行操作8份,分别加入氨试液
Antitussive and anti-asthma oral liquid is made up of Ephedra, Schisandra, Asarum and Glycyrrhizae. Determination of ephedrine in the preparation of colorimetry has been reported [1 ~ 3], this article using alkalinization extraction - colorimetric method to determine the content of ephedrine in Zhikepingchuan oral liquid, the operation is simple, fast, and the results are satisfactory. 1 Instrument and reagent Shimadzu UV-2100 UV spectrophotometer; Ephedrine Hydrochloride (Xinjiang Heshuo Ephedrine Products Co., Ltd., Lot No. 990301, Shandong Pharmaceutical Co., Ltd., content 99.3%); Ephedrine hydrochloride reference substance ( China National Institute for the Control of Pharmaceutical and Biological Products, 714-9202); Zhike Pingchuan Oral Liquid (Hospital Preparation); Carbon disulfide (AR); Other reagents are of analytical grade. 2 Extraction method selection Ephedrine hydrochloride solution (200μg · mL-1) 5.0mL, placed in the separatory funnel, parallel operation of 8 copies, were added to the ammonia test solution