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目的:研究窒息新生儿中黄疸发生情况及窒息程度与血清胆红素水平的关系。方法:以110例窒息新生儿为研究对象,其中重度窒息组42例,轻度窒息组68例,101例无窒息新生儿为对照组,比较三组黄疸发生及治疗情况,研究窒息程度与黄疸的相关性。结果:三组黄疸发生率分别为31.7%、17.6%、4.8%,差异有统计学意义(P<0.05);三组血清胆红素水平分别为205.7μmol/L、131.2μmol/L、43.2μmol/L,差异均有统计学意义(P<0.05)。其中窒息组黄疸发生率、血清胆红素水平较低,窒息新生儿Apgar评分与血清胆红素水平呈负相关(r=-7.228,P<0.05),窒息新生儿黄疸消退时间较长。结论:窒息新生儿血清胆红素偏低与胆红素消耗有关,对于窒息新生儿血清胆红素水平应结合临床综合考虑,做出正确评估。
Objective: To study the incidence of jaundice and the relationship between asphyxia and serum bilirubin level in neonates with asphyxia. Methods: A total of 110 neonates with asphyxia were enrolled in this study. Among them, 42 patients with severe asphyxia, 68 patients with mild asphyxia and 101 neonates without asphyxia served as the control group. The incidence and treatment of jaundice in the three groups were compared. The degree of asphyxia and jaundice Relevance. Results: The incidence of jaundice in the three groups was 31.7%, 17.6% and 4.8%, respectively, with significant difference (P <0.05). Serum bilirubin levels were 205.7μmol / L, 131.2μmol / L, 43.2μmol / L, the differences were statistically significant (P <0.05). Among them, the incidence of jaundice and serum bilirubin in asphyxia group were lower, Apgar score of asphyxia neonatorum was negatively correlated with serum bilirubin level (r = -7.228, P <0.05), and jaundice subsided longer in asphyxia neonatorum. Conclusion: Serum bilirubin in asphyxia neonates is related to the consumption of bilirubin. Serum bilirubin level in neonates with asphyxia should be correctly evaluated in combination with clinical considerations.