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目的分析病毒学检验在乙肝患者中的效果,提升乙肝的临床确诊率,并为乙肝的防治提供参考。方法选取医院2012年3月-2014年3月收治的乙肝患者82例作为观察组,并选取医院同期体检的健康者82例作为对照组,分别对2组对象的血清进行乙肝病毒学指标检测,包括乙型肝炎病毒e抗原(HBe Ag)、e抗体(HRe Ab)、表面抗原(HBs Ag)、表面抗体(HBs Ab)和核心抗体(HBc Ab),同时统计阳性率。结果观察组和对照组HBe Ag、HRe Ab、HBs Ag、HBs Ab、HBc Ab各指标的阳性率分别为48.8%、63.4%、82.9%、25.6%、74.4%和15.9%、25.6%、32.9%、4.88%、36.6%,2组比较差异有统计学意义(P<0.05)。结论对乙肝患者实施病毒学详细检验,不仅使乙肝病毒学5项指标得以精确检查,对乙肝的诊断、病情评估、防治及预后均具有极为重要的意义。
Objective To analyze the effect of virological test in patients with hepatitis B and to improve the clinical diagnosis of hepatitis B and to provide reference for the prevention and treatment of hepatitis B. Methods Eighty-two patients with hepatitis B admitted from March 2012 to March 2014 in our hospital were selected as the observation group and 82 healthy subjects in the same period of the hospital were selected as the control group. Serum samples from two groups were tested for hepatitis B virus (HBV) Including hepatitis B virus e antigen (HBe Ag), e antibody (HRe Ab), surface antigen (HBs Ag), surface antibody (HBs Ab) and core antibody (HBc Ab), while counting the positive rate. Results The positive rates of HBe Ag, HRe Ab, HBs Ag, HBs Ab and HBc Ab in the observation and control groups were 48.8%, 63.4%, 82.9%, 25.6%, 74.4% and 15.9%, 25.6% and 32.9% , 4.88% and 36.6%, respectively. There was significant difference between the two groups (P <0.05). Conclusions The detailed virological examination of patients with hepatitis B not only makes accurate examination of 5 indicators of hepatitis B virus, but also plays an important role in the diagnosis, assessment, prevention and prognosis of hepatitis B patients.