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目的:对自身抗体联合检测在系统性红斑狼疮诊断中的临床价值进行探讨。方法:选取从2011年12月~2013年12月收治的90位系统性红斑狼疮患者,设为观察组,选取同期其他类风湿疾病的60位患者设为对照组,在抽取静脉血以后,将血清分离,并将其敏感性差异进行对比。结果:在抗rRNP抗体、抗dsDNA抗体、抗Sm抗体以及AnuA阳性概率方面,观察组明显高于对照组,P<0.05,其差异有统计学意义。结论:在系统性红斑狼疮的诊断中,抗rRNP抗体、抗dsDNA抗体、抗Sm抗体以及AnuA有着重要的作用,采取联合检测方式,能使准确诊断系统性红斑狼疮的概率得到提高。
Objective: To explore the clinical value of autoantibodies in the diagnosis of systemic lupus erythematosus. Methods: Totally 90 patients with systemic lupus erythematosus who were admitted from December 2011 to December 2013 were selected as the observation group. Sixty patients with other rheumatic diseases in the same period were selected as the control group. After the venous blood was drawn, Sera were separated and their differences in sensitivity were compared. Results: In the anti-rRNP antibody, anti-dsDNA antibody, anti-Sm antibody and AnuA positive probability, the observation group was significantly higher than the control group, P <0.05, the difference was statistically significant. Conclusion: In the diagnosis of systemic lupus erythematosus, anti-rRNP antibody, anti-dsDNA antibody, anti-Sm antibody and AnuA play an important role in the detection of systemic lupus erythematosus can increase the probability of accurate diagnosis of systemic lupus erythematosus.