许多资料表明,病毒能引起对宿主免疫反应性(IR)的非特异性调节作用,抑制或增强对异种抗原的免疫应答。 1908年Von Pirquet首先报道这种现象,他观察到麻疹患者对结核菌素的迟发型皮肤超敏感性暂时消失。但是,直到20世纪后半期才对其他病毒感染时的IR的非特异性调节作用作深入的研究。属于至少13个科的40多种病毒可引起对异种抗原的免疫应答的非特异性改变。人类 Many sources indicate that the virus can cause a nonspecific modulation of host immunoreactivity (IR) and inhibit or enhance the immune response to xenoantigen. Von Pirquet first reported this phenomenon in 1908 and he observed a temporary loss of delayed-type hypersensitivity to tuberculin in measles patients. However, it was not until the second half of the 20th century that further studies were conducted on the nonspecific modulation of IR at other viral infections. More than 40 viruses belonging to at least 13 families can cause nonspecific changes in the immune response to xenoantigens. Humanity