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目的 观察羊膜移植术在急性期及瘢痕期眼表损伤中的治疗效果。方法 选择眼表理化生物损伤急性期 10例 ( 14眼 ) ,及瘢痕期 6例 ( 7眼 ) ,行新鲜及保存羊膜移植 ,部分联合板层或穿透性角膜移植 ,随访 6～ 2 2月。结果 急性期者无一例发生角膜融解或睑球粘连 ;瘢痕期严重睑球粘连者中 1例术后部分复发 ;联合角膜移植者均未见新生血管长入。结论 羊膜移植对急性期和瘢痕期眼表损伤防止角膜融解、睑球粘连 ,改良眼表基底及重建眼表上皮均有肯定效果。
Objective To observe the therapeutic effect of amniotic membrane transplantation in ocular surface lesions in acute phase and scar phase. Methods Ten cases (14 eyes) were selected during the acute stage of ocular electro-chemical physical injury, and 6 cases (7 eyes) were treated with fresh and preserved amniotic membrane transplantation, some combined with lamellar or penetrating keratoplasty. The patients were followed up from February to February . Results No cases of acute corneal thalamus or symblepharon were observed in the acute stage. One case of severe symblepharon in the scar stage was partially recurred. No corneal neovascularization was found in the corneal allografts. Conclusions Amniotic membrane transplantation has definite effect on ocular surface injury in acute stage and scar stage, preventing corneal thalamus, symblepharon, improving ocular surface and reconstructing ocular surface epithelium.