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在神经管畸形高发的北方城乡地区、低发的南方城乡地区,从1991年6月到1992年6月,采用称量法入户对1 921名婚检妇女进行了膳食调查,分析了其膳食蛋氨酸含量,结果显示平均膳食蛋氨酸含量为1153.55mg/d,其95％范围为565.3mg/d～2 353.94mg/d;南方妇女膳食蛋氨酸含量为1 382.16mg/d,北方妇女为 932.62mg/d(P<0.05);城市妇女膳食蛋氨酸含量为1 187.49mg/d,农村为1 117.44mg/d(P<0.05);一年四季膳食蛋氨酸含量无明显差异(P>0.05)。膳食蛋氨酸含量与神经管畸形在地区分布上的一致性,提示蛋氨酸缺乏是否为神经管畸形的病因之一值得进一步研究。
In the northern urban and rural areas with high incidence of neural tube defects and the low incidence of urban and rural areas in the south, from June 1991 to June 1992, 1 921 premarital women were surveyed by weighing method, and their dietary methionine The results showed that the average dietary methionine content was 1153.55mg / d, the 95% range was 565.3mg / d ~ 3593.94mg / d, the dietary methionine content was 1 382.16mg / d in the south and 932.62mg / d in the north (P <0.05). The dietary methionine content of urban women was 1 187.49 mg / d and that of rural residents was 1 117.44 mg / d (P <0.05). There was no significant difference in dietary methionine content between urban and rural areas (P> 0.05). Dietary methionine content and neural tube defects in the regional distribution of consistency, suggesting that methionine deficiency is one of the causes of neural tube defects deserve further study.