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目的探讨喉罩通气全凭吸入七氟醚在老年乳腺癌改良根治术麻醉中的应用价值。方法选取2013年4月至2015年4月沈阳市胸科医院收治的44例行改良根治术的老年乳腺癌患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各22例。对照组患者予以传统静脉复合麻醉诱导,观察组患者采用单纯高氧七氟醚实施麻醉诱导,比较两组患者麻醉诱导时间、麻醉维持时间、麻醉唤醒时间、喉罩拔除时间以及不同时间段心率、平均动脉压、血氧饱和度。结果观察组患者的喉罩拔除时间明显短于对照组,差异有统计学意义(P<0.05);置入喉罩时,观察组患者的平均动脉压明显高于对照组,两组患者的平均动脉压较其他时点均显著降低,差异均有统计学意义(均P<0.05),其他时点两组患者的平均动脉压差异均无统计学意义(均P>0.05);置入喉罩时,观察组患者的心率明显高于对照组,差异有统计学意义(P<0.05),其他时点内两组患者的心率差异均无统计学意义(均P>0.05)。结论对行改良根治术的老年乳腺癌患者实施喉罩通气全凭吸入七氟醚麻醉,临床效果显著,可维持血流动力学稳定,且安全可靠。
Objective To evaluate the value of laryngeal mask ventilation for inhalation of sevoflurane in modified radical mastectomy for elderly patients with breast cancer. Methods Forty-four elderly patients with breast cancer underwent modified radical mastectomy from April 2013 to April 2015 in Shenyang Chest Hospital. The patients were divided into control group and observation group by random number table example. Patients in the control group were induced by traditional intravenous anesthesia induction. Patients in the observation group were induced by simple hyperoxic sevoflurane anesthesia. The induction time, anesthesia duration, anesthesia wake time, laryngeal mask extraction time and heart rate, Mean arterial pressure, oxygen saturation. Results The duration of laryngeal mask removal in the observation group was significantly shorter than that in the control group (P <0.05). When the laryngeal mask was inserted, the mean arterial pressure in the observation group was significantly higher than that in the control group. The mean Arterial pressure were significantly lower than those at other time points (all P <0.05), while at other time points there was no significant difference in mean arterial pressure between the two groups (all P> 0.05) , The heart rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). There was no significant difference in heart rate between the two groups at other time points (all P> 0.05). Conclusion The implementation of laryngeal mask ventilation in elderly patients with breast cancer who underwent modified radical mastectomy is complete with inhalation of sevoflurane anesthesia. The clinical effect is remarkable, and the hemodynamic stability can be maintained and the method is safe and reliable.