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近几年来氨苄青霉素应用很普遍,不合理的应用时有发生,故结合临床实际情况商讨几个问题.一、选药问题氨苄青霉素对革兰氏阳性球菌、杆菌及革兰阴性球菌的作用不亚于青霉素 G,对肠球菌的作用可能稍强些.对革兰氏阴性杆菌比青霉素 G 强,但不如卡那霉素、庆大霉素和多粘霉素。也有人认为对青霉素敏感的菌株,半合成的青霉素的抗菌力均不及青霉素 G。本品在临床上可用于革兰氏阴性杆菌引起的呼吸道感染、胆道感染、败血症及伤寒等,但对 b 型流感杆菌及绿脓杆菌无效.对于革兰氏阳性菌引起的疾病还是用青霉素 G为宜,不应盲目应用本品,因为青霉素 G 对革兰氏
In recent years, the application of ampicillin is very common, unreasonable applications have occurred, it combined with clinical practice to discuss several issues.One, the problem of drug selection ampicillin on Gram-positive cocci, bacilli and gram-negative cocci role Sub-penicillin G, the role of Enterococci may be slightly stronger. Gram-negative bacilli than penicillin G, but not as good as kanamycin, gentamicin and polymyxin. Some people think that the penicillin-sensitive strains, semi-synthetic penicillin antibacterial activity are less than penicillin G. This product can be used clinically for Gram-negative bacilli caused by respiratory infections, biliary tract infections, sepsis and typhoid fever, but not on the type b influenza bacilli and Pseudomonas aeruginosa invalid for Gram-positive bacteria caused by penicillin G Appropriate, should not blindly apply this product, because of penicillin G against Gram