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下面部脂肪室在老化过程中变化趋势不同，下面部年轻化方案应针对脂肪室具体变化综合评估，并掌握下面部血管神经解剖，提高临床应用安全性。近年来，影像学方法在面部脂肪室研究中的应用，有助于更深入理解下面部衰老的相关变化，为下面部容量恢复有效性及安全性提供新的思路。该文就下面部老化过程中相关脂肪室的衰老变化及应用解剖作一综述，有助于术者更深入理解下面部衰老的相关变化，为基于“脂肪再平衡”理论进行的下面部年轻化方案提供新的理论依据及临床启示。“,”The trends of age-associated change regarding lower facial fat compartments were different. The lower facial rejuvenation should be comprehensively evaluated according to the specific changes of the fat compartments, and master the anatomy of the lower blood vessels and nerves to improve the safety of clinical application. In recent years, the application of imaging methods in the study of facial fat compartments has helped to better understand the changes related to the aging of the lower part and provide new ideas for the effectiveness and safety of the volume recovery of the lower part. This article reviews the aging changes and applied anatomy of the fat compartments in the process of aging of the lower part, which helps surgeons to understand the related changes of aging of the lower part more deeply, and provides new theoretical basis and clinical enlightenment for the rejuvenationof the lower part based on the theory of fat rebalance.