The climatic variations since the Little Ice Age recorded in the Guliya Ice Core are discussed based on glacial δ18O and accumulation records in the Guliya Ice Core. Several obvious climate fluctuation events since 1570 can be observed according to the records. In the past 400 years, the 17th and 19th centuries are relatively cool periods with less precipitation, and the 18th and 20th centuries are relatively warm periods with high precipitation. The study has also revealed the close relationship between temperature and precipitation on the plateau. Warming corresponds to high precipitation and cooling corresponds to less precipitation, which is related with the influence of monsoon on this region. The climatic variations since the Little Ice Age recorded in the Guliya Ice Core are based on glacial δ18O and accumulation records in the Guliya Ice Core. Several obvious climate fluctuations events since 1570 can be observed under the records. In the past 400 years, the 17th and 19th centuries are relatively cool periods with less precipitation, and the 18th and 20th centuries are quite warm periods with high precipitation. The study has also revealed the close relationship between temperature and precipitation on the plateau. Warming correspondence to high precipitation and cooling corresponds to less precipitation, which is related with the influence of monsoon on this region.