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目的探讨异甘草酸镁治疗抗结核药物性肝损伤82例的疗效。方法 82例经血清生化指标确认的由于使用抗结核药物引起药物性肝损伤患者,给予5%葡萄糖针250 ml+异甘草酸镁针150 mg,1次/d,静脉滴注,疗程3周,对其疗效进行分析。结果 79例患者治愈,血清生化指标均正常,3例无效,总有效率96.34%,除1例患者出现眼睑浮肿,无高血压、低钾血症等发生。结论异甘草酸镁治疗抗结核药物性肝损伤,治疗后预后较好,副作用少。
Objective To investigate the effect of magnesium isoglycyrrhizinate on 82 cases of anti-TB drug-induced liver injury. Methods Eighty-two patients with drug-induced liver injury who were confirmed by serum biochemical indexes were given 250% 5% glucose and magnesium isoglycyrrhizinate 150 mg once a day for 3 weeks. The curative effect was evaluated analysis. Results 79 patients were cured, serum biochemical indicators were normal, 3 cases were ineffective, the total efficiency of 96.34%, except 1 case of eyelid edema, no hypertension, hypokalemia and so on. Conclusion Isoglycate magnesium treatment of anti-TB drug-induced liver injury, the prognosis is good, less side effects.