幽门螺杆菌(Helicobacter pylori,H.pylori)是一类定植在人类胃黏膜的革兰阴性杆菌,主要通过“人-人”、“粪-口”等途径进行传播。H.pylori感染主要始于儿童期,其自发性清除非常少见,如不进行抗微生物治疗,H.pylori可在人类胃黏膜上持续定植几十年。全世界有超过50%的人口感染了H.pylori。自发现以来,大量研究表明,H.pylori感染与慢性胃炎、消化性 Helicobacter pylori (Helicobacter pylori, H.pylori) is a group of Gram-negative bacilli colonized in human gastric mucosa, mainly through “human-man ”, “fecal- oral ” and other means of transmission. H. pylori infection mainly starts in childhood, its spontaneous clearance is very rare, if not antimicrobial treatment, H.pylori can continue to colonize the human gastric mucosa for decades. More than 50% of the world’s population is infected with H.pylori. Since the discovery, a large number of studies have shown that H.pylori infection and chronic gastritis, digestive