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[目的]观察刺五加液联合纳洛酮治疗急性脑梗死疗效。[方法]将44例住院脑梗死患者按照随机数字表随机分为两组,两组均常规降颅压、改善脑细胞代谢药物治疗,不用其他降纤酶、低分子肝素等影响凝血纤溶系统药物。对照组20例复方丹参液加低分子右旋糖酐及改善脑细胞代谢基础治疗。治疗组24例刺五加液100mL,静滴,2次/d;纳洛酮4mg,静滴/d。均15d为1疗程。观察病残程度、神经功能缺损评分。治疗2疗程(30d)判定疗效。[结果]治疗组基本痊愈14例,显效7例,有效2例,无效1例,总有效率95.83%。对照组基本痊愈5例,显效6例,有效4例,无效5例,总有效率75.00%。治疗组疗效优于对照组。[结论]刺五加液联合纳洛酮治疗急性脑梗死疗效满意。
[Objective] To observe the efficacy of acanthopanax liquid plus naloxone in the treatment of acute cerebral infarction. [Methods] Forty-four patients with cerebral infarction in hospital were randomly divided into two groups according to a random number table. Both groups were routinely given intracranial pressure to improve the metabolism of brain cells. No other defibrase and LMWH were involved in coagulation and fibrinolysis drug. Control group, 20 cases of compound Danshen solution plus low molecular weight dextran and improve brain cell metabolism basic treatment. Treatment group, 24 cases of Acanthopanax liquid 100mL, intravenous infusion, 2 times / d; naloxone 4mg, intravenous drip / d. 15d for a course of treatment. Observe the degree of sickness, neurological deficit score. Treatment 2 course of treatment (30d) to determine the efficacy. [Results] The treatment group basically cured in 14 cases, markedly effective in 7 cases, effective in 2 cases, ineffective in 1 case, the total effective rate was 95.83%. The control group basically recovered in 5 cases, markedly effective in 6 cases, effective in 4 cases, ineffective in 5 cases, the total effective rate was 75.00%. The treatment group than the control group. [Conclusion] Acanthopanax senticosus plus naloxone is effective in treating acute cerebral infarction.