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我们观察血管紧张素转换酶抑制剂(ACEI)-依那普利对非胰岛素依赖型糖尿病(NIDDM)合并糖尿病肾病(DN)患者尿蛋白排泄、血压、血糖及肾功能的影响,现报道如下。 1 对象和方法 1.1 对象 DN患者39例.NIDDM诊断符合WHO标准(1985)。男18例,女21例,年龄33～79岁,平均(54.3±7.2)岁;病程3～25年,平均(12.3±5.8)年。并根据尿蛋白排泄率分为早期DN(尿白蛋白排泄率30～300mg/24h)16例。临床期DN(持续性蛋白尿、尿白蛋白>300mg/24h)18例。根据血尿素氮、肌酐增高诊为终末期肾衰6例。所有患者无急慢性肾炎、尿路感
We observed the effects of angiotensin converting enzyme inhibitor (ACE inhibitor) -enapril on urinary protein excretion, blood pressure, blood glucose, and renal function in patients with non-insulin dependent diabetes mellitus (DN) complicated with diabetic nephropathy (DN) and are reported below. 1 Subjects and methods 1.1 object DN patients in 39. NIDDM diagnosis in line with WHO standards (1985). There were 18 males and 21 females, aged from 33 to 79 years, with an average of 54.3 ± 7.2 years. The course of disease ranged from 3 to 25 years (mean, 12.3 ± 5.8 years). And according to urinary protein excretion rate is divided into early DN (urinary albumin excretion rate 30 ~ 300mg / 24h) in 16 cases. Clinical DN (persistent proteinuria, urinary albumin> 300mg / 24h) in 18 cases. According to blood urea nitrogen, creatinine increased diagnosis of end-stage renal failure in 6 cases. All patients without acute and chronic nephritis, urinary tract flu