目的：探讨以脑立体定向术治疗震颤麻痹、癫痫、癌性疼痛、慢性精神病及颅内金属异物的方法和疗效。方法：用多功能脑立体定向仪对不同疾病毁损其不同的核团。结果：震颤麻痹１６６例共１８２次手术中治愈１３例次，显效１４５例次，有效１１例次，无效１２例次，死亡１例，有效率达９２９％；癫痫１８例，显效１１例，有效４例，无效３例，有效率达８３３％；癌性痛疼５例均显效；精神病３例，显效２例，有效１例；颅内异物２例均治愈。结论：脑立体定向术对以上疾病均取得了较为满意及良好的疗效，总有效率达９２４％，并且比传统开颅术简便安全 Objective: To explore the method and efficacy of cerebral stereotactic surgery for Parkinsonism, epilepsy, cancer pain, chronic psychosis and intracranial metal foreign body. METHODS: Multifunctional brain stereotactic devices were used to destroy their different nuclei for different diseases. Results: Paralysis paralysis 166 cases of 182 operations were cured 13 cases, markedly effective 145 cases, effective in 11 cases, 12 cases ineffective, 1 died, the effective rate was 92  9%; 18 cases of epilepsy, markedly effective in 11 cases , Effective in 4 cases, invalid in 3 cases, the effective rate was 83  3%; 5 cases of cancerous pain were markedly effective; mental illness in 3 cases, 2 cases markedly effective in 1 case; 2 cases of intracranial foreign body were cured. Conclusion: Stereotaxy has achieved satisfactory results and good curative effects on the above diseases, with a total effective rate of 924%, which is more simple and safe than traditional craniotomy