论文部分内容阅读
目的：探讨阴茎粒细胞肉瘤的临床表现、病理特点及诊治方法。方法回顾分析1例阴茎粒细胞肉瘤患者的临床资料、免疫病理、诊断和治疗,并复习相关文献。结果患者一年前行阴茎肿物局部切除，术后辅以5个疗程的化疗及中药治疗后结发感染患者双侧腹股沟及盆腔淋巴结转移，拒绝根治性阴茎切除，出院，5个月后死亡。肿瘤组织免疫组化检测 MPO、CD43、CD117及 Vimentin 均为阳性，CD3，CD20、CgA、S-100和CK均为阴性。结论原发性粒细胞肉瘤是一种由未成熟髄样细胞构成的恶性肿瘤，发生于阴茎者罕见。诊断和鉴别诊断主要依靠肿瘤织的免疫组化，早期对受累及的器官根治性切除，再加放疗或化疗可提高疗效。“,”Objective To discuss the pathological characteristics,clinical manifestations, diagnosis and treatment of penis granulocytic sarcoma. Methods A case of penis granulocyte sarcoma was retrospectively analyzed the clinical data,immune pathology, diagnosis and treatmen, and review the relevant literature. Results A year ago was excised the penis neoplasm and 5- course of chemotherapy. After treatment with traditional Chinese medicine. The patient was ccoured bilateral inguinal and pelvic lymph node metastasis, 5 months after death. Tumor tissue immunohistochemical detection of MPO, CD43, CD117 and Vimentin were positive, CD3, CD20, CgA, S- 100 and CK were negative. Conclusion Primary granulocytic sarcoma was a malignant tumor composing of immature spinal cord cells and was very rare in penis into tumor. The diagnosis and differential diagnosis of primary granulocytic sarcoma mainly depended on immunohistochemistry analysis. Early radical resection of the affected organs plus radiotherapy or chemotherapy can improve therapeutic effect.