Trichloroethylene (TCE) is a major pollutant that affects both occupational and general environments [1] . The liver is an important target organ of TCE [1] . Substantial efforts and remarkable progress into understanding TCE cytotoxicity have been made in cultured liver cells. However, the molecular mechanisms by which TCE induces Trichlorethylene (TCE) is a major pollutant that affects both occupational and general environments [1]. The liver is an important target organ of TCE [1]. Substantial efforts and remarkable progress into understanding TCE cytotoxicity have been made in cultured liver cells. However, , the molecular mechanisms by which TCE induces