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目的探讨低剂量对比剂联合低辐射剂量(双低剂量)CT肾动脉成像的可行性。方法将36例临床疑有肾动脉病变的患者随机分为3组:常规剂量组、双低剂量A组和双低剂量B组,每组各12例。双低剂量A组:320 mgI/mL碘佛醇0.8 mL/kg,120 kV,自动毫安,SD15;双低剂量B组:320 mgI/mL碘佛醇0.8 mL/kg,120 kV,自动毫安,SD20;常规剂量组:300 mgI/mL碘海醇1.3 mL/kg,120 kV,自动毫安,SD10。其他扫描参数一致,注射速率3.5 mL/s,采用Sure start造影剂追踪技术。将原始薄层图像在工作站进行容积再现(VR)、最大密度投影(MIP)三维重组。将图像传到NFPACS,由两名经验丰富的医师在盲法下对图像评分并记录CTDIvol(CT溶剂量指数)。SPSS16.0软件进行统计学分析。结果双低剂量A组和B组CTDIvol明显降低,分别为常规剂量组的65%和43%。每公斤体重有效碘用量明显降低,为常规剂量组的66%。对于肾动脉主干和一级分支的显示,各组差异无统计学意义。双低剂量A组对肾动脉二级分支显示良好。双低剂量B组对于肾动脉二级分支的显示能力差。结论双低剂量A组的图像满足临床诊断需要,低剂量对比剂联合低辐射剂量(双低剂量)CT肾动脉成像具有可行性。
Objective To investigate the feasibility of low-dose contrast agent combined with low-dose (double-dose) CT renal artery imaging. Methods Thirty-six patients with suspected renal artery disease were randomly divided into 3 groups: conventional dose group, double low dose group and double low dose group B, 12 in each group. Double low dose group A: 320 mgI / mL ioversol 0.8 mL / kg, 120 kV, auto milliamps, SD15; double low dose Group B: 320 mgI / mL ioversol 0.8 mL / kg, 120 kV, Safety, SD20; conventional dose group: 300 mgI / mL iohexol 1.3 mL / kg, 120 kV, automatic milliamps, SD10. The other scan parameters were consistent with an injection rate of 3.5 mL / s using Sure start contrast agent tracking. The original thin-layer images were reconstructed by volume (VR) and maximum density projection (MIP) at the workstation. The images were passed to NFPACS, where images were scored and recorded by two experienced physicians under blinded CTDIvol (CT Solubility Index). SPSS16.0 software for statistical analysis. Results The double-dose CTDIvol of group A and group B decreased significantly, which was 65% and 43% respectively of the conventional dose group. The amount of available iodine per kg of body weight was significantly reduced, 66% of the conventional dose group. Renal artery trunk and a branch of the show, the differences were not statistically significant. Double low-dose group A renal artery secondary branch showed good. The double low dose group B had poor ability to display the secondary branches of the renal artery. Conclusion The images of double low dose group A meet the needs of clinical diagnosis. Low dose contrast agent combined with low dose radiation (double low dose) CT renal artery imaging is feasible.