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目的观察老年人鼻咽癌同步放化疗毒副反应。方法将21例老年人Ⅱ至Ⅳa期鼻咽癌同步放化疗;放射治疗剂量鼻咽部70～76Gy,颈部预防50Gy,有阳性淋巴结66～70Gy;同期顺铂40mg/M2,1次/周。结果:Ⅲ度胃肠反应28.5%,Ⅲ度骨髓抑制23.8%,需要停止化疗占43%。结论:老年人鼻咽癌同步放化疗的毒副反应较严重,耐受性差。
Objective To observe the side effects of concurrent radiotherapy and chemotherapy in the elderly with nasopharyngeal carcinoma. Methods 21 cases of elderly Ⅱ ~ Ⅳa nasopharyngeal carcinoma concurrent chemoradiotherapy; radiation dose of nasopharyngeal 70 ~ 76Gy, neck prevention 50Gy, positive lymph nodes 66 ~ 70Gy; cisplatin 40mg / M2, 1 times / week . Results: Ⅲ degree gastrointestinal reaction 28.5%, Ⅲ degree bone marrow suppression 23.8%, need to stop the chemotherapy accounted for 43%. Conclusions: The side effects of concurrent chemoradiotherapy in elderly patients with nasopharyngeal carcinoma are more serious and poorly tolerated.