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为了观察慢性支气管炎单纯型和喘息型患者的白细胞移动有无差别,应用Bovden小室法检测了慢性支气管炎单纯型和喘息型患者外周血白细胞随机移动(RM)及趋化移动(chtM)。结果:两实验组患者RM及chtM均较健康对照组明显增高(P均<0.01),提示白细胞移动改变在慢性支气管炎的发生和发展中具有一定意义。喘息型组的RM及chtM又较单纯型组明显增高(P<0.01),可能为喘息型患者出现临床喘息的内在原因之一。
In order to observe whether there is any difference in leukocyte migration between simple and asthmatic patients with chronic bronchitis, the peripheral blood leucocytes of chronic bronchitis patients with simple bronchitis and asthmatic patients were detected by Bovden chamber method for random movement (RM) and chemotactic migration (chtM). Results: The RM and chtM in both experimental groups were significantly higher than those in healthy controls (all P <0.01), suggesting that leukocyte migration has some significance in the occurrence and development of chronic bronchitis. The wheezing group had significantly higher levels of RM and chtM than the simple type (P <0.01), which may be one of the internal causes of asthmatic wheezing.