目的 分析hiv/aids患者死亡原因,并探讨cd4+ t淋巴细胞计数与死亡的相关性.方法 回顾性分析上海市公共卫生临床中心1996年1月至2007年9月所有hiv/aids死亡患者的相关资料,并对相关指标进行t检验.结果 89例死亡患者感染hiv的途径以异性性传播、输血及血制品为主.cd4+t淋巴细胞计数不同,死亡的主要原因也存在一定差异,计数越高,因上消化道出血等非aids相关机会感染死亡的比例越大.各种原因导致的严重肺部感染是造成患者死亡的最主要原因,其中多种病原微生物同时感染所占比例最高.结论 各种机会感染仍是hiv/aids患者死亡的主要原因,临床上需参考cd4+ t淋巴细胞计数及患者的具体情况,及时采取相应的措施以降低患者的死亡率.; abstract：; objective to analyze the causes of death for 89 hiv/aids patients,and the association of cd4+ t lymphocyte counts with the mortality.methods data were collected from 89 deceased patients who were admitted to shanghai public health clinical center from jan 1996 to sep 2007,and were retrospectively analyzed with t-test.results heterosexual,blood transfusion and blood products were the major transmission routs for 89 deceased hiv/aids patients.the primary causes of death varied with different levels of cd4+ t lymphocyte counts.with higher cd4+t lymphocyte counts,patients were more likely to die from non-aids-related opportunistic infections such as upper digestive tract hemorrhage.serious pulmonary infection induced by various etiologies was the primary cause of death.co-infections of multiple etiologics were often seen in these death cases.conclusion opportunistic infection is the primary cause of death for hiv/aids patients.appropriate therapies should be based on cd4+ t lymphocyte counts and patients' specific conditions to reduce the mortality.