目的　了解阿莫西林联合甲氰咪胍在促进十二指肠球部溃疡 (DU)愈合及防止复发的作用。方法　用阿莫西林联合甲氰咪胍为治疗组 (A组 ) ,并设单纯甲氰咪胍治疗组为对照组 (B组 )观察。结果　A组在HP清除率、溃疡愈合率、有效率及溃疡复发率均优于B组 ,差异有显著性。结论　在基层医院或因选药受经济条件限制时 ,联合上述两药 ,同样可以收到好的效果 Objective To understand the effect of amoxicillin combined with cimetidine in promoting duodenal ulcer (DU) healing and preventing recurrence. Methods Amoxicillin combined with cimetidine for the treatment group (A group), and set the cetanidine-treated group as the control group (B group) observed. Results The clearance rate of HP, the healing rate of ulcer, the effective rate and the recurrence rate of ulcer in group A were better than those in group B, the difference was significant. Conclusions In the primary hospital or due to drug selection due to economic constraints, the combination of these two drugs, the same can receive good results