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白塞病葡萄膜炎是葡萄膜炎中难治的类型之一,多表现为全葡萄膜炎,对视力影响大,病情易反复,通常需要传统免疫抑制剂,如糖皮质激素、环孢素、苯丁酸氮芥、环磷酰胺等联合使用控制病情,长期使用毒性作用和不良反应大.干扰素、抗肿瘤坏死因子、抗白细胞介素及其受体等新型生物制剂为白塞病葡萄膜炎的治疗提供了新的治疗手段.本文就白塞病葡萄膜炎的传统免疫抑制剂治疗、生物制剂治疗以及二者的治疗效果比较进行综述.“,”Ocular Beh(c)et disease,which usually presents as panuveitis,with characteristic of vision impairment and relapse,is one of the most refractory uveitis entities.Usually,one or more conventional immunosuppressive agents,such as glucocorticoid,ciclosporin,chlorambucil,cyclophosphamide,etc,are needed in disease management.However,long-term use of immunosuppressive agents would result in severe adverse effects.New biologics,such as interferon,antitumor necrosis factor agents,interleukin or its receptor antagonists,provide new therapeutic approaches to the treatment for this disease.This paper reviewed the conventional therapies and biologics applied in ocular Beh(c)et disease.