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作者应用~(192)Ir源胆管内照射治疗3例胆管癌,将线源留置在前端为盲端的导管内,把此导管经皮经肝插入胆管内腔,~(192)Ir线源腔内照射剂量目前尚无最佳剂量标准,作者考虑到胆管癌对放疗敏感性低,采用距线源5mm处30Gy腔内照射及30Gy外部照射。对腔内照射的适应证尚无定论,Prempree等认为胆管癌小于1.5cm时只腔内照射,大于1.5cm则并用外照射。一般胆管癌发现时多为进行性癌,一般认为腔内照射并外照射者比单纯外照射平均生存期延长,并用腔内照射者平均生存月数为15个月,2年生存率为25%。单纯外照射平均生存
The authors treated ~(192)Ir from intraductal cholecystectomy in 3 cases of cholangiocarcinoma. The line source was placed in the catheter with a blind tip and the catheter was percutaneously inserted into the lumen of the bile duct. The ~(192)Ir line source cavity There is no optimal dose standard for the irradiation dose. The authors consider that the sensitivity of cholangiocarcinoma to radiotherapy is low, using 30 Gy intraluminal irradiation and 30 Gy external irradiation at a distance of 5 mm from the source. The indications for intraluminal irradiation have not been conclusive. Prempree et al. considered that only when the bile duct cancer is less than 1.5 cm, only intraluminal irradiation, and when it is greater than 1.5 cm, external irradiation is used. In general, cholangiocarcinoma is often diagnosed as progressive cancer, and it is generally believed that the average survival time of intraluminal irradiation and external irradiation is longer than that of external irradiation alone. The average number of months of survival for intraluminal irradiation is 15 months, and the 2-year survival rate is 25%. . Simple external exposure