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哺乳动物的Toll样受体(Toll-like receptor,TLR)是一种重要的模式识别受体,TLR3是Toll样受体家族中的一员,与病毒感染密切相关。本文就TLR3相关信号转导途径与病毒感染及凋亡作一综述。
Mammalian Toll-like receptor (TLR) is an important pattern recognition receptor. TLR3 is a member of the Toll-like receptor family, which is closely related to virus infection. This review summarizes TLR3-related signal transduction pathway and viral infection and apoptosis.