心力衰竭是可以引起大片肝细胞坏死,尽管不怎么常见。在多数情况下,肝细胞大片坏死的临床表现常同心功能不全混杂在一起。我们报告的这六例患者,均患有慢性心力衰竭,并有急性循环衰竭的发作,而引起了大片肝细胞坏死和暴发性肝衰竭。暴发性肝衰竭的表现为肝性脑病,黄疸、凝血酶元时间明显延长。这些表现在急性循环衰竭发作后经过1～3天的间隔才出现,这时,这些患者的血液动力学的情况巳经恢复到发 Heart failure can cause large hepatocellular necrosis, though less common. In most cases, the clinical manifestations of hepatocellular necrosis often congenital dysfunction mixed together. All six of our patients reported had chronic heart failure and had episodes of acute circulatory failure, causing massive hepatocellular necrosis and fulminant hepatic failure. Fulminant hepatic failure manifests as hepatic encephalopathy, jaundice, and prolonged prothrombin time. These manifestations occur at intervals of 1 to 3 days after the onset of acute circulatory failure and the hemodynamic status of these patients has now recovered