林可霉素是临床上广泛应用的抗生素,其常见的不良反应为消化道反应,表现有恶心、呕吐、舌炎和肛门瘙痒等,有时可致转氨酶升高和黄疸.长期使用可致伪膜性肠炎,大剂量推注可引起心搏骤停和血压下降.对林可霉素导致的过敏反应和神经系统症状等少见不良反应,近来国内文献时有报道,为引起广大医务人员的重视,笔者综述如下. Lincomycin is clinically widely used antibiotics, its common adverse reactions are gastrointestinal reactions, manifested nausea, vomiting, glossitis and anal itching, and sometimes can cause elevated aminotransferases and jaundice. Long-term use can cause pseudomembranous Enteritis, high-dose bolus can cause cardiac arrest and blood pressure drop.And Lincomycin-induced allergic reactions and neurological symptoms and other rare adverse reactions, the recent domestic literature has been reported, to arouse the attention of the general medical staff, The author summarized as follows.