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目的报告1例鼻中隔透明细胞软骨肉瘤并复习相关文献。方法结合光镜、免疫组化对1例透明细胞软骨肉瘤进行形态学观察并复习相关文献。结果本例鼻中隔透明细胞软骨肉瘤影像学上表现为鼻中隔分叶状肿块,中央可见钙化影,形态学上由透明细胞和软骨母细胞样细胞构成,间质为软骨样基质,形成分叶状结构。免疫组化显示肿瘤细胞表达Vim和S100。结论鼻中隔透明细胞软骨肉瘤诊断要结合形态学与免疫表型特点,鉴别诊断尤为重要。
Objective To report 1 case of clear cell chondrosarcoma of nasal septum and to review relevant literature. Methods Combined with light microscope and immunohistochemistry, 1 case of clear cell chondrosarcoma was observed morphologically and relevant literature was reviewed. Results In this case, the clear serous chondrosarcoma of the nasal septum was imaged with subcuticular nasal septum masses with central calcification. Morphologically, it was composed of clear cells and chondroblastoid cells. The stroma was a cartilage-like matrix, forming lobulated structures . Immunohistochemistry showed that tumor cells expressed Vim and S100. Conclusion The diagnosis of clear cell chondrosarcoma of nasal septum should be combined with morphological and immunophenotypic characteristics, differential diagnosis is particularly important.