为合成酚酸取代的葡萄糖苷类天然产物,以全乙酰溴代葡萄糖为起始物,与4-苄氧基苄醇反应成苷,脱乙酰基后,选择性地在葡萄糖4,6-位形成亚苄基,2,3-位羟基用苄基保护,脱去亚苄基得到裸露葡萄糖4,6-位羟基的化合物(4-苄氧基苄基)-2,3-二-O-苄基-β-D-吡喃葡萄糖苷(7),该化合物可作为合成4,6-位选择性取代的葡萄糖衍生物的有效中间体。 For the synthesis of phenolic acid-substituted glucoside natural products, all acetyl acetyl glucoside as a starting material, with 4-benzyloxybenzyl alcohol into glycosides, deacetylation, selective glucose 4,6-position Forming a benzylidene group, protecting the 2,3-hydroxyl group with a benzyl group and removing the benzylidene group to obtain a compound (4-benzyloxybenzyl) -2,3-di-O- Benzyl-β-D-glucopyranoside (7), which is useful as an effective intermediate for the synthesis of 4,6-position selectively substituted glucose derivatives.