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目的:观察探讨糖尿病病人肾功能改变与血糖及血脂的关系,总结其临床指导意义。方法:选取我院2013年2月至2013年3月社区体检非胰岛素依赖型糖尿病(NIDDM)的患者100例,分别检测其肾功能指标,按照晨尿微量白蛋白(urinarymicroalbumin,U-Alb)检测结果分为肾功能指标正常组41例和肾功能指标异常组59例,观察对比两组的血糖及血脂指标差异。结果:异常组患者胆固醇(Tch)、甘油三酯(TG)、空腹血糖(FBG)均高于正常组(P<0.05),具有统计学意义;异常组患者的尿微量白蛋白水平与Tch、TG、FBG水平间存在显著的相关性(r=0.71,0.46,0.46,P<0.05),具有统计学意义。结论:糖尿病病人肾功能改变与血糖及血脂间有明显的正相关关系,因此,早期降低和控制血糖、血脂水平,对于阻碍糖尿病患者肾功能恶化,降低糖尿病肾病发生率,有积极的临床意义。
Objective: To investigate the relationship between the changes of renal function and blood glucose and blood lipids in diabetic patients and to summarize its clinical significance. Methods: A total of 100 patients with non-insulin-dependent diabetes mellitus (NIDDM) from February 2013 to March 2013 in our hospital were enrolled in this study. Their renal function parameters were measured. Urinary microalbumin (U-Alb) The results were divided into normal control group of 41 cases of renal function and abnormal renal function group of 59 cases, observed the difference between the two groups of blood glucose and blood lipid indicators. Results: The levels of cholesterol, triglyceride and fasting blood glucose (FBG) in patients with abnormal group were significantly higher than those in normal group (P <0.05), and the levels of urine microalbumin in patients with abnormal group were significantly different from those in patients with abnormal group (Tch, TG, FBG levels there is a significant correlation (r = 0.71,0.46,0.46, P <0.05), with statistical significance. CONCLUSION: The changes of renal function in diabetic patients have obvious positive correlation with blood glucose and blood lipid. Therefore, reducing and controlling blood glucose and blood lipid level early has a positive clinical significance in preventing the deterioration of renal function and reducing the incidence of diabetic nephropathy in diabetic patients.