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目的探讨门诊处方中质子泵抑制剂(PPIs)的使用情况,为临床合理用药提供参考。方法收集某院门诊2014年1月至6月的处方,对含有PPIs的处方全面记录相关信息,按《处方管理办法》相关规定,对其进行合理性分析。结果本次共抽取PPIs的处方6 778张,其中不合理处方有2 020张,占29.8%,不合理用药发生频率较高的是适应证掌握不当、药物配伍不合理、药物用法不合理等。结论建议临床医师严格掌握用药指征和用法用量,使PPIs的使用更加合理、规范。
Objective To investigate the use of proton pump inhibitors (PPIs) in outpatient prescriptions and provide a reference for clinical rational drug use. Methods The prescriptions of a hospital outpatient department from January to June in 2014 were collected. The prescriptions containing PPIs were recorded in a comprehensive way. The rationality of the prescriptions was analyzed according to the relevant provisions of the “prescription management approach”. Results A total of 6 778 prescriptions for PPIs were obtained, of which 2,020 were unreasonable prescriptions and 29.8% were unreasonable prescriptions. The higher incidence of irrational use of drugs was due to improper indications of indications, unreasonable drug compatibility and irrational use of drugs. Conclusions It is suggested that clinicians strictly control the indications and usage of drugs, making the use of PPIs more reasonable and standardized.