美国每年出生350万人,其中婴儿的母亲患育癫痫的占0.33％,即有11,550人,她们大多数在妊娠期间服了抗惊药,如果抗惊药有明显的致畸作用,则每年会大量有缺陷的儿童诞生,大多数抗惊药结构类似,因此这一类药很可能都有致畸作用。 1963年Mullers-Kuppers报告过一名三岁半的男孩是小头畸形、粘膜下腭裂、严重的言语障碍,发育商为60,男孩的母亲在 In the United States, 3.5 million people are born each year, of whom 0.33% are infants and mothers with epilepsy, or 11,550. Most of them take anti-shock drugs during pregnancy. If the anticonvulsant has obvious teratogenic effects, the annual meeting A large number of defective children were born, most of the anti-shock drug structure is similar, so this type of medicine are likely to have teratogenic effects. Muller-Kuppers reported in 1963 that a three-and-a-half-year-old boy had microcephaly, submucosal cleft palate, severe speech impairment, a developmental quotient of 60 and a boy’s mother at