本实验研究注射D-氨基半乳糖(Galn)引起大鼠肝损伤后血清游离氨基酸浓度变化,实验结果表明:测定的21种氨基酸中最突出并有判断预后价值的氨基酸是精、鸟、组和酪氨酸。注射Galn 后24～72小时死亡的动物,精氨酸和组氨酸极度降低,而鸟氨酸和酪氨酸则显著升高;若Galn 所致肝损伤相对较轻,不致引起动物死亡时,则出现精氨酸浓度升高,鸟氨酸浓度显著下降,而酪和组氨酸浓度无变化。 The experimental study of D-galactosamine (Galn) induced liver injury in rats after free amino acid concentration changes, the experimental results show that: the determination of the 21 kinds of amino acids in the most prominent and prognostic value of amino acids are fine, birds, and Tyrosine. Arginine and histidine were significantly decreased in animals that died 24 to 72 hours after injection of Galn, whereas ornithine and tyrosine were significantly increased; if the liver injury caused by Galn was relatively light and did not cause death in animals, Arginine concentration was increased, ornithine concentration decreased significantly, while the cheese and histidine concentration did not change.