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Frick.O.L.等(1977)首先观察到病毒感染和变态反应性疾病发病的关系。他们发现13例病孩中有12例发病是由上呼吸道感染所诱发,表现为IgE水平的增高和白细胞组织胺的释放。1978年Perelmu-tter报道6例非特应性患者感染呼吸道病毒后显示恢复期血中IgE含量比急性期低(下降35-87％)。本室病毒组进行流行
Frick.O.L. (1977) first observed the relationship between viral infection and the incidence of allergic diseases. They found that 12 of 13 patients were diagnosed as having upper respiratory tract infections and showed elevated IgE levels and leukocyte histamine release. Perelmu-tter reported in 6 cases of non-atopic patients infected with respiratory virus showed that convalescent blood IgE levels lower than the acute phase (down 35-87%). Viruses in this room are popular