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目的探讨陀螺旋转式钴60立体定向放射治疗系统(陀螺旋转式γ刀)分次治疗脑转移瘤的方法和近期疗效。方法应用上海伽玛星科技发展有限公司的GMX B型陀螺旋转式钴60立体定向放射治疗系统,分次治疗70例脑转移瘤患者,其中单病灶38例,多病灶32例,肿瘤直径0.6~3.3cm,多靶点联合照射,用50%~60%等剂量曲线包绕,周边处方剂量3000~3850cGy,中心6000~7700cGy,单次剂量300~450cGy,1次/日,5次/周,一疗程8~12次。结果随访期3~24个月,3个月内有效控制率91.4%,生存率94.3%,6个月生存率74.3%,12个月47.1%,24个月17.1%。中位生存期9.6个月。结论陀螺旋转式伽玛刀分次治疗脑转移瘤近期疗效满意,副作用小,是脑转移瘤综合治疗的一种有效手段之一。
Objective To study the method and short-term curative effect of gyro-rotating cobalt-60 stereotactic radiotherapy system (gyroscopic γ-knife) in treating brain metastases. Methods GMG B type gyroscope cobalt 60 stereotactic radiotherapy system was applied to Shanghai Gammastar Technology Development Co., Ltd., 70 patients with brain metastases were divided into groups, of which 38 were single lesions, 32 were multiple lesions and the diameter of tumor was 0.6 ~ 3.3cm, multi-target combined irradiation, with 50% to 60% isodose curve wrapped around the prescription dose of 3000 ~ 3850cGy, center 6000 ~ 7700cGy, single dose of 300 ~ 450cGy, 1 times / day, 5 times / A course of 8 to 12 times. Results The follow-up period was 3-24 months. The effective control rate was 91.4% within 3 months, the survival rate was 94.3%, the 6-month survival rate was 74.3%, the 12-month rate was 47.1%, and the 24-month rate was 17.1%. The median survival time of 9.6 months. Conclusions Gynecologic Gynecologic Gynecologic Oncosis is one of the effective methods for the comprehensive treatment of brain metastases.