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目的探讨功能磁共振成像(fMRI)在运动区脑胶质瘤的临床应用价值。方法 13例脑胶质瘤患者(治疗组)术前行常规MRI和fMRI检查,根据术前肿瘤影像学评估,分别设计手术方案切除肿瘤,并行术后随访。10例正常志愿者进行常规MRI和fMRI检查作为正常对照(对照组)。结果治疗组fMRI表现为手运动功能区被挤压、移位;对照组fMRI表现为手运动功能区显示良好。术后两周随访,治疗组患者Karnofsky评分恢复至平均95分,与术前比较有统计学差异(P<0.05)。结论 fMRI对邻近脑运动功能区胶质瘤患者手术前评价具有重要临床意义,可指导外科治疗,提高手术疗效,减少术后并发症。
Objective To investigate the clinical value of functional magnetic resonance imaging (fMRI) in glioma of motor region. Methods Thirteen patients with glioma (treatment group) underwent routine MRI and fMRI before operation. According to the preoperative tumor imaging evaluation, the surgical plans were respectively designed to excise the tumors and followed up. Ten normal volunteers underwent routine MRI and fMRI examination as normal controls (control group). Results The fMRI of the treatment group showed that the hand motor function area was squeezed and shifted, while the fMRI performance of the control group showed good motor function. After two weeks of follow-up, the Karnofsky score of the treatment group recovered to an average of 95 points, which was significantly different from that before operation (P <0.05). Conclusion The fMRI has important clinical significance in the preoperative evaluation of patients with gliomas in brain functional areas. It can guide the surgical treatment, improve the curative effect and reduce the postoperative complications.